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The Medical Detectives is a weekly podcast where medicine meets mystery—told by the very people who’ve lived it. Hosted by orthopedic surgeon Dr. Erin Nance and content creator Anna O’Brien, each episode unravels strange and surprising medical tales from the people who lived through them. Think of it as a detective story—only here, the clues are hidden in blood tests, x-rays, and patient files.
From curious, unsolved diagnoses to behind-the-scenes accounts of what really goes on in hospital corridors, Anna and Dr. Nance guide you through the ups, downs, and jaw-dropping moments of life in the medical world. Dr. Nance brings her professional insight as a practicing physician committed to uncovering disparities in healthcare, while Anna shares her experiences as a patient navigating a complex system.
In every episode you’ll hear first hand stories from guests who’ve confronted real medical puzzles on the relentless search for answers in a system that doesn’t always have them. Dr. Nance brings her insider expertise, while Anna uses her own patient experiences to spot the heart of every story. Together, they explore the suspense, the drama, and sometimes even the humor, behind solving these real-life medical mysteries.
Whether you’re a curious mind, an avid true-crime fan, or someone who’s been left in the dark by confusing diagnoses, The Medical Detectives shines a light on the unexplained. Listen in each week to learn, to question, and to be amazed by the strange but true cases that prove sometimes the most gripping mysteries unfold in hospital corridors.
The Medical Detectives is a weekly podcast where medicine meets mystery—told by the very people who’ve lived it. Hosted by orthopedic surgeon Dr. Erin Nance and content creator Anna O’Brien, each episode unravels strange and surprising medical tales from the people who lived through them. Think of it as a detective story—only here, the clues are hidden in blood tests, x-rays, and patient files.
From curious, unsolved diagnoses to behind-the-scenes accounts of what really goes on in hospital corridors, Anna and Dr. Nance guide you through the ups, downs, and jaw-dropping moments of life in the medical world. Dr. Nance brings her professional insight as a practicing physician committed to uncovering disparities in healthcare, while Anna shares her experiences as a patient navigating a complex system.
In every episode you’ll hear first hand stories from guests who’ve confronted real medical puzzles on the relentless search for answers in a system that doesn’t always have them. Dr. Nance brings her insider expertise, while Anna uses her own patient experiences to spot the heart of every story. Together, they explore the suspense, the drama, and sometimes even the humor, behind solving these real-life medical mysteries.
Whether you’re a curious mind, an avid true-crime fan, or someone who’s been left in the dark by confusing diagnoses, The Medical Detectives shines a light on the unexplained. Listen in each week to learn, to question, and to be amazed by the strange but true cases that prove sometimes the most gripping mysteries unfold in hospital corridors.
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Recent Hosts, Guests & Topics
Here's a quick summary of the last 5 episodes on The Medical Detectives.
Hosts
Dr. Erin Nance
Anna O'Brien
Previous Guests
Angela
Angela is the wife of Trevor, the male patient featured in this episode. She played a crucial role in advocating for Trevor's health and well-being throughout his medical journey, demonstrating the importance of patient advocacy in navigating complex healthcare challenges.
Angela is the wife of Trevor, the male patient featured in this episode. She played a crucial role in advocating for Trevor's health and well-being throughout his medical journey, demonstrating the importance of patient advocacy in navigating complex healthcare challenges.
Chelle
Chelle is a patient who lived with daily headaches, nausea, numbness, and overwhelming pressure in her head for nearly 35 years. Her symptoms were often dismissed as anxiety or depression until a medical crisis involving her child prompted her to trust her instincts and seek answers. Chelle's journey highlights the challenges of misdiagnosis and the importance of advocating for one's health.
Chelle is a patient who lived with daily headaches, nausea, numbness, and overwhelming pressure in her head for nearly 35 years. Her symptoms were often dismissed as anxiety or depression until a medical crisis involving her child prompted her to trust her instincts and seek answers. Chelle's journey highlights the challenges of misdiagnosis and the importance of advocating for one's health.
Rita
Rita is a young mother and nurse who experienced a decade-long medical mystery characterized by severe symptoms, misdiagnosis, and dismissal from healthcare professionals. Her journey highlights the challenges of medical gaslighting and the impact of sexism within the healthcare system, particularly in military medical contexts. After years of suffering and self-doubt, Rita finally received a diagnosis that validated her experiences.
Rita is a young mother and nurse who experienced a decade-long medical mystery characterized by severe symptoms, misdiagnosis, and dismissal from healthcare professionals. Her journey highlights the challenges of medical gaslighting and the impact of sexism within the healthcare system, particularly in military medical contexts. After years of suffering and self-doubt, Rita finally received a diagnosis that validated her experiences.
Leah
Leah grew up without seeing a real doctor, learning instead from her homeopath mother how to listen to her body. As an adult, she faced numerous health challenges, including being told she was allergic to the sun, iron, and bread. Her medical journey took a dramatic turn when she ended up in the ER on her 40th birthday, experiencing severe symptoms that baffled doctors. Leah's case became notable due to the rare diagnosis she ultimately received, which highlighted the struggles of being believed in the medical system.
Leah grew up without seeing a real doctor, learning instead from her homeopath mother how to listen to her body. As an adult, she faced numerous health challenges, including being told she was allergic to the sun, iron, and bread. Her medical journey took a dramatic turn when she ended up in the ER on her 40th birthday, experiencing severe symptoms that baffled doctors. Leah's case became notable due to the rare diagnosis she ultimately received, which highlighted the struggles of being believed in the medical system.
Bethany
Bethany is a former professional dancer who faced significant health challenges throughout her career. After experiencing chronic pain and a series of misdiagnoses, she became an advocate for herself in the medical system. Her journey highlights the struggles of being dismissed by healthcare professionals and the importance of perseverance and self-advocacy in seeking answers for one's health issues.
Bethany is a former professional dancer who faced significant health challenges throughout her career. After experiencing chronic pain and a series of misdiagnoses, she became an advocate for herself in the medical system. Her journey highlights the struggles of being dismissed by healthcare professionals and the importance of perseverance and self-advocacy in seeking answers for one's health issues.
Topics Discussed
Guillain-Barr
addiction
gallbladder surgery
medical advocacy
diagnosis
Johns Hopkins
headaches
nausea
numbness
misdiagnosis
self-doubt
medical crisis
trusting instincts
medical mystery
medical gaslighting
sexism in healthcare
systemic failures
military medical system
misdiagnoses
rare disease
orthopedic surgeon
ER
purple urine
allergic reactions
chronic pain
self-advocacy
perseverance
professional dancer
YouTube Channel
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Episodes
Here's the recent few episodes on The Medical Detectives.
0:001:16:53
Trevor & Angela's Story: The Wife vs. The White Coat
This week on The Medical Detectives, Erin and Anna tackle their first-ever male patient story, delivered by the one person who never stopped believing him: his wife, Angela. From childhood Guillain-Barr and a hidden battle with addiction to a whirlwind romance and marriage, Trevors life derails when relentless vomiting and mysterious unexplained ER visits lead to gallbladder surgery, and still no answers. It isnt until a desperate trip to Johns Hopkins that a sharp-eyed clinician finally diagnoses him, revealing how dangerous medical labels and overlooked side effects can be. Join us as we explore the power of advocacy, the damage of judgment, and what it really takes to be heard in your own care.
Have a medical mystery or story of your own? Send it to [email protected].
***The information provided on the medical detectives is for informational and entertainment purposes only and should not be considered medical advice. While we may feature licensed medical professionals, including doctors, we are not your personal doctors and no doctor patient relationship is established by listening to this podcast or interacting with our content.
All discussions are general in nature and may not apply to your specific health situation. Always seek the advice of a qualified healthcare professional before making any medical decisions or taking any action based on the content of this podcast. Never disregard professional medical advice or delay seeking treatment because of something you have heard on this show
If you are experiencing a medical emergency, please contact emergency services immediately or consult a qualified healthcare pro***
This week on The Medical Detectives, Erin and Anna tackle their first-ever male patient story, delivered by the one person who never stopped believing him: his wife, Angela. From childhood Guillain-Barr and a hidden battle with addiction to a whirlwind romance and marriage, Trevors life derails when relentless vomiting and mysterious unexplained ER visits lead to gallbladder surgery, and still no answers. It isnt until a desperate trip to Johns Hopkins that a sharp-eyed clinician finally diagnoses him, revealing how dangerous medical labels and overlooked side effects can be. Join us as we explore the power of advocacy, the damage of judgment, and what it really takes to be heard in your own care.
Have a medical mystery or story of your own? Send it to [email protected].
***The information provided on the medical detectives is for informational and entertainment purposes only and should not be considered medical advice. While we may feature licensed medical professionals, including doctors, we are not your personal doctors and no doctor patient relationship is established by listening to this podcast or interacting with our content.
All discussions are general in nature and may not apply to your specific health situation. Always seek the advice of a qualified healthcare professional before making any medical decisions or taking any action based on the content of this podcast. Never disregard professional medical advice or delay seeking treatment because of something you have heard on this show
If you are experiencing a medical emergency, please contact emergency services immediately or consult a qualified healthcare pro***
For nearly 35 years Chelle lived with daily headaches, nausea, numbness, and overwhelming pressure in her head—symptoms repeatedly dismissed as anxiety or depression. But when her child’s medical crisis taught her to trust her instincts, she finally pushed for answers. In this episode, Chelle shares her decades-long journey of misdiagnosis, self-doubt, and dismissal before discovering the true cause.
Have a medical mystery or story of your own? Send it to [email protected].
***The information provided on the medical detectives is for informational and entertainment purposes only and should not be considered medical advice. While we may feature licensed medical professionals, including doctors, we are not your personal doctors and no doctor patient relationship is established by listening to this podcast or interacting with our content.
All discussions are general in nature and may not apply to your specific health situation. Always seek the advice of a qualified healthcare professional before making any medical decisions or taking any action based on the content of this podcast. Never disregard professional medical advice or delay seeking treatment because of something you have heard on this show
If you are experiencing a medical emergency, please contact emergency services immediately or consult a qualified healthcare pro***
For nearly 35 years Chelle lived with daily headaches, nausea, numbness, and overwhelming pressure in her head—symptoms repeatedly dismissed as anxiety or depression. But when her child’s medical crisis taught her to trust her instincts, she finally pushed for answers. In this episode, Chelle shares her decades-long journey of misdiagnosis, self-doubt, and dismissal before discovering the true cause.
Have a medical mystery or story of your own? Send it to [email protected].
***The information provided on the medical detectives is for informational and entertainment purposes only and should not be considered medical advice. While we may feature licensed medical professionals, including doctors, we are not your personal doctors and no doctor patient relationship is established by listening to this podcast or interacting with our content.
All discussions are general in nature and may not apply to your specific health situation. Always seek the advice of a qualified healthcare professional before making any medical decisions or taking any action based on the content of this podcast. Never disregard professional medical advice or delay seeking treatment because of something you have heard on this show
If you are experiencing a medical emergency, please contact emergency services immediately or consult a qualified healthcare pro***
0:001:51:05
Rita's Story: All in Her Head
Hosts
Hosts of this podcast episode
Dr. Erin NanceAnna O'Brien
Guests
Guests of this podcast episode
Rita
Keywords
Keywords of this podcast episode
medical mysterymisdiagnosismedical gaslightingsexism in healthcaresystemic failuresmilitary medical system
In this deeply emotional and eye-opening episode of Medical Detectives, we sit down with Rita, whose medical mystery spanned nearly a decade of pain, misdiagnosis, and dismissal. From being a young mother and nurse with a sudden onset of terrifying symptoms to being told she just needed candy or mental health care, Rita’s story highlights the devastating impact of medical gaslighting, sexism in healthcare, and systemic failures—particularly within the military medical system. Through years of relentless symptoms and self-doubt, Rita finally receives a diagnosis that validates everything she’s endured.
Have a medical mystery or story of your own? Send it to [email protected].
***The information provided on the medical detectives is for informational and entertainment purposes only and should not be considered medical advice. While we may feature licensed medical professionals, including doctors, we are not your personal doctors and no doctor patient relationship is established by listening to this podcast or interacting with our content.
All discussions are general in nature and may not apply to your specific health situation. Always seek the advice of a qualified healthcare professional before making any medical decisions or taking any action based on the content of this podcast. Never disregard professional medical advice or delay seeking treatment because of something you have heard on this show
If you are experiencing a medical emergency, please contact emergency services immediately or consult a qualified healthcare pro***
In this deeply emotional and eye-opening episode of Medical Detectives, we sit down with Rita, whose medical mystery spanned nearly a decade of pain, misdiagnosis, and dismissal. From being a young mother and nurse with a sudden onset of terrifying symptoms to being told she just needed candy or mental health care, Rita’s story highlights the devastating impact of medical gaslighting, sexism in healthcare, and systemic failures—particularly within the military medical system. Through years of relentless symptoms and self-doubt, Rita finally receives a diagnosis that validates everything she’s endured.
Have a medical mystery or story of your own? Send it to [email protected].
***The information provided on the medical detectives is for informational and entertainment purposes only and should not be considered medical advice. While we may feature licensed medical professionals, including doctors, we are not your personal doctors and no doctor patient relationship is established by listening to this podcast or interacting with our content.
All discussions are general in nature and may not apply to your specific health situation. Always seek the advice of a qualified healthcare professional before making any medical decisions or taking any action based on the content of this podcast. Never disregard professional medical advice or delay seeking treatment because of something you have heard on this show
If you are experiencing a medical emergency, please contact emergency services immediately or consult a qualified healthcare pro***
0:001:23:16
Leah's Story: The Vampire Diagnosis
Hosts
Hosts of this podcast episode
Dr. Erin NanceAnna O'Brien
Guests
Guests of this podcast episode
Leah
Keywords
Keywords of this podcast episode
medical mysterymisdiagnosesrare diseaseorthopedic surgeonERpurple urineallergic reactions
Leah grew up never seeing a real doctor, but learning from her homeopath mom how to listen to her body. As an adult, she was told she was allergic to the sun, iron, and bread. But when she landed in the ER on her 40th birthday, vomiting, in unbearable pain, and with purple urine, doctors were perplexed. Every test was coming back negative, and all of a sudden she felt like she was in an episode of House. Finally,an orthopedic surgeon remembered an obscure disease from medical school...
This is a medical mystery for the books, with misdiagnoses, near-death moments, and a diagnosis so rare it made Leah a teaching case. Part comedy, part chaos, and all too real for anyone who’s ever had to fight to be believed.
Have a medical mystery or story of your own? Send it to [email protected].
***The information provided on the medical detectives is for informational and entertainment purposes only and should not be considered medical advice. While we may feature licensed medical professionals, including doctors, we are not your personal doctors and no doctor patient relationship is established by listening to this podcast or interacting with our content.
All discussions are general in nature and may not apply to your specific health situation. Always seek the advice of a qualified healthcare professional before making any medical decisions or taking any action based on the content of this podcast. Never disregard professional medical advice or delay seeking treatment because of something you have heard on this show
If you are experiencing a medical emergency, please contact emergency services immediately or consult a qualified healthcare pro***
Leah grew up never seeing a real doctor, but learning from her homeopath mom how to listen to her body. As an adult, she was told she was allergic to the sun, iron, and bread. But when she landed in the ER on her 40th birthday, vomiting, in unbearable pain, and with purple urine, doctors were perplexed. Every test was coming back negative, and all of a sudden she felt like she was in an episode of House. Finally,an orthopedic surgeon remembered an obscure disease from medical school...
This is a medical mystery for the books, with misdiagnoses, near-death moments, and a diagnosis so rare it made Leah a teaching case. Part comedy, part chaos, and all too real for anyone who’s ever had to fight to be believed.
Have a medical mystery or story of your own? Send it to [email protected].
***The information provided on the medical detectives is for informational and entertainment purposes only and should not be considered medical advice. While we may feature licensed medical professionals, including doctors, we are not your personal doctors and no doctor patient relationship is established by listening to this podcast or interacting with our content.
All discussions are general in nature and may not apply to your specific health situation. Always seek the advice of a qualified healthcare professional before making any medical decisions or taking any action based on the content of this podcast. Never disregard professional medical advice or delay seeking treatment because of something you have heard on this show
If you are experiencing a medical emergency, please contact emergency services immediately or consult a qualified healthcare pro***
In this extraordinary episode of The Medical Detectives, we meet Bethany, a former professional dancer whose body, once built for movement, began betraying her in small, painful ways that no one could explain. What started as stiffness and toe pain evolved into years of misdiagnoses, dismissed symptoms, and being told it was all in her head.
Over two decades, Bethany endured chronic pain, gave up her dream career, and pushed through three pregnancies — all while quietly suffering with a condition no one could name. It wasn’t until a late-night scroll on Facebook and a self-driven Google rabbit hole that she discovered what no doctor had seen.
This episode has it all — ballerinas, babies, and dinosaurs (yes, dinosaurs). But at its core, it’s about perseverance, medical gaslighting, and the power of self-advocacy. Bethany’s story is a testament to trusting your gut, pushing for answers, and the life-changing power of finally being believed.
Have a medical mystery or story of your own? Send it to [email protected].
***The information provided on the medical detectives is for informational and entertainment purposes only and should not be considered medical advice. While we may feature licensed medical professionals, including doctors, we are not your personal doctors and no doctor patient relationship is established by listening to this podcast or interacting with our content.
All discussions are general in nature and may not apply to your specific health situation. Always seek the advice of a qualified healthcare professional before making any medical decisions or taking any action based on the content of this podcast. Never disregard professional medical advice or delay seeking treatment because of something you have heard on this show
If you are experiencing a medical emergency, please contact emergency services immediately or consult a qualified healthcare pro***
In this extraordinary episode of The Medical Detectives, we meet Bethany, a former professional dancer whose body, once built for movement, began betraying her in small, painful ways that no one could explain. What started as stiffness and toe pain evolved into years of misdiagnoses, dismissed symptoms, and being told it was all in her head.
Over two decades, Bethany endured chronic pain, gave up her dream career, and pushed through three pregnancies — all while quietly suffering with a condition no one could name. It wasn’t until a late-night scroll on Facebook and a self-driven Google rabbit hole that she discovered what no doctor had seen.
This episode has it all — ballerinas, babies, and dinosaurs (yes, dinosaurs). But at its core, it’s about perseverance, medical gaslighting, and the power of self-advocacy. Bethany’s story is a testament to trusting your gut, pushing for answers, and the life-changing power of finally being believed.
Have a medical mystery or story of your own? Send it to [email protected].
***The information provided on the medical detectives is for informational and entertainment purposes only and should not be considered medical advice. While we may feature licensed medical professionals, including doctors, we are not your personal doctors and no doctor patient relationship is established by listening to this podcast or interacting with our content.
All discussions are general in nature and may not apply to your specific health situation. Always seek the advice of a qualified healthcare professional before making any medical decisions or taking any action based on the content of this podcast. Never disregard professional medical advice or delay seeking treatment because of something you have heard on this show
If you are experiencing a medical emergency, please contact emergency services immediately or consult a qualified healthcare pro***
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