Dhru Purohit Show

This episode is brought to you by Bon Charge, One Skin, and Branch Basics.

Over 95% of Americans are deficient in one key nutrient: fiber. And yet, fiber plays a powerful role in overall healthsupporting weight loss, better sleep, and increased satiety. Todays guest takes a deep dive into fiber, gut health, and why adding more plants to your diet is one of the best things you can do for your well-being.

Today on The Dhru Purohit Show, Dhru sits down with Dr. Will Bulsiewicz to discuss why increasing the diversity of plants in your diet is crucial for gut and overall health. Dr. Bulsiewicz shares his top tips and go-to recipe for anyone beginning their journey toward more fiber and plant diversity. He also explores concerns surrounding the increasing use of GLP-1 medications without a long-term plan and identifies the most effective practices for achieving sustainable weight loss. If youre looking for a deep dive into what damages the gut microbiomeand how to truly optimize your gut healththis episode is for you.

Dr. Will Bulsiewicz is a board-certified gastroenterologist, an internationally recognized expert in gut health, and the bestselling author of Fiber Fueled and The Fiber Fueled Cookbook. He serves as U.S. Medical Director and Scientific Advisor at ZOE, has published over 20 peer-reviewed articles, has presented to Congress and the USDA, and has taught gut health to over 10,000 students. Dr. B earned his MD from Georgetown, trained at Northwestern and UNC, where he was chief fellow, and completed an NIH-funded epidemiology fellowship at UNCs Gillings School of Global Public Health.

In this episode, Dhru and Dr. Bulsiewicz dive into:

Increasing the diversity of plants in your diet (00:30)

Research on the significance of adding diversity to your diet (3:42)

Starting the day with a morning smoothie as a best practice for diversity (9:30)

Base ingredients for smoothies and beginner-friendly plant additions (17:10)

Personalizing the right amount of fiber for your gut microbiome (25:41)

Emulsifiers added to plant-based meals (28:03)

The connection between fiber and GLP-1 (36:54)

Intense food noise, cravings, and long-term drug dependency (43:59)

A tiered approach to weight loss (48:17)

Alcohol and the least damaging options from a gut perspective (1:09:24)

Marijuana use and its impact on health (1:14:25)

The controversy behind the MAHA movement (1:19:29)

Fermented foods and their effects on the microbiome (1:31:44)

Tier-ranking what damages the gut microbiome (1:40:12)

Concerns about the carnivore diet and Dr. Bulsiewiczs observations (1:53:59)

Dr. Bulsiewiczs prebiotics and the journey to build a better microbiome (1:57:49)

Strengthening intuition and learning to trust your gut (2:04:03)

Also mentioned in this episode:

ZOE

38Tera: Dr. Bulsiewiczs prebiotic

For more on Dr. Bulsiewicz, follow him on Instagram, Facebook, LinkedIn, and his Website.

This episode is brought to you by Bon Charge, One Skin, and Branch Basics.

Right now, Bon Charge is offering my community 15% off; just go to boncharge.com/DHRU and use coupon code DHRU to save 15%.

Right now, One Skin is offering my community 15% off; just go to oneskin.co and use coupon code DHRU to save 15% and give your skin the scientifically proven, gentle care it deserves.

Right now, Branch Basics is offering 15% off the Premium Starter Kit; just go to branchbasics.com and use coupon code DHRU. Make 2025 your cleanest, healthiest year yet with Branch Basics!

Sign up for Dhrus Try This Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is brought to you by Maui Nui, Levels, and Ollie.

When we think about chronic disease and vital organs, the liver isnt always the first that comes to mindbut it should be. The liver plays a role in nearly every metabolic process in the body, from stabilizing blood sugar levels to converting amino acids into usable fuel. Todays guest joins the podcast for a deep dive into how optimizing liver health is key to supporting overall health.

Today on The Dhru Purohit Show, Dhru sits down with Kristin Kirkpatrick to explore the livers vital role in detoxification, the rise of fatty liver disease, and how liver health impacts overall mortality. They break down the connection between diet and liver function, debunk myths about dietary fat, and examine the effects of ultra-processed foods and artificial sweeteners. Kristin shares the benefits of coffee, muscle mass, and blood sugar balance for metabolic health, along with key liver-supportive foods, lifestyle tips, and insights into GLP-1 medications for those with obesity and liver issues.

In this episode, Dhru and Kristin dive into:

The shocking rates of non-alcoholic fatty liver disease (00:00)

Understanding fatty liver disease and its twelve major risk factors (2:51)

Why Americans are at greater risk (7:50)

The crucial role the liver plays in the body (13:28)

The phases of detoxification from environmental toxins (18:18)

Research linking fatty liver disease to increased mortality risk (22:28)

The earlier onset of fatty liver disease in todays population (27:15)

Why carbohydrates may be more to blame than fat (27:54)

The impact of Diet Cola, artificial sweeteners, and foods to avoid (32:01)

Twelve liver-friendly foods to prioritize (48:31)

The importance of building and maintaining muscle mass (58:01)

Lifestyle recommendations for managing fatty liver disease (1:05:31)

The role of physical activity in liver health (1:08:31)

Understanding GLP-1 medications and their effects (1:11:53)

Final thoughts on liver health and nutrition (1:18:31)

Also mentioned in this episode:

Kristins Presentation Slides

Regenerative Health Book

For more on Kristin, follow her on Facebook, Instagram, X/Twitter, Pinterest, Youtube, LinkedIn, and her Website.

This episode is brought to you by Maui Nui,Levels, and Ollie.

Right now, Maui Nui Venison is offering my listeners a limited collection of my favorite cuts and products. Just go to mauinuivenison.com/dhru to secure your access now but hurry, supply is limited!

Right now, Levels is offering my listeners an additional 2 FREE months of the Levels annual Membership when you use my link: levels.link/DHRU. Make moves on your metabolic health with Levels today.

Want to give your dog the best in clean eating? Take the online quiz and introduce Ollie to your pet. Right now, Ollie is offering 60% off your first box of meals when you subscribe today! Just head to Ollie.com, use the code DHRU, and youll get 60% off your first box of meals in your subscription. Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is brought to you by Momentous, Cozy Earth, and Levels.

In today’s world, addiction takes many forms—whether it’s alcohol, drugs, social media, or people-pleasing. Certain key factors drive these behaviors and make breaking the cycle incredibly challenging. Today’s guest offers powerful insights into brain health and psychology, explaining why these patterns emerge and how we can begin to unhook from them.

On this episode of The Dhru Purohit Show, Dhru sits down with psychologist and addiction expert Dr. Adi Jaffe. Dr. Jaffe breaks down the “hook” that keeps us stuck in addictive behaviors and explores the root causes that draw us back to them. He takes a deep dive into shame—the true fuel behind addiction—and explains why people-pleasing is one of the hardest patterns to break. He also shares his own powerful journey of overcoming addiction and highlights the importance of holding onto beliefs that serve us—and letting go of those that don’t.

Dr. Adi Jaffe is a UCLA-trained psychologist and a leading expert on mental health, addiction, and relationships. Once a meth addict and drug dealer, his life changed after a SWAT arrest and jail sentence. Now the author of The Abstinence Myth and Unhooked, Dr. Jaffe challenges traditional addiction treatment and leads IGNTD, an organization helping former inmates find support for addiction and mental health. His work has been featured on CNN, Fox, NBC, and Psychology Today.

In this episode, Dhru and Dr. Jaffe dive into:

The hook beneath addiction (00:00)

What you gain by holding onto your addiction (5:47)

The deeper roots of people-pleasing (7:15)

Dhru and Dr. Jaffe's personal stories with people-pleasing (11:58)

The SPARO Method explained (19:38)

Dr. Jaffe's personal addiction story and how Unhooked was created (24:40)

Why shame is the true fuel behind addiction (36:02)

The hooks and stimulants that fueled Dr. Jaffe's past addictions (41:22)

Fixed mindset vs. growth mindset (50:21)

The capacity for change: being reactive vs. proactive (55:01)

How Dr. Jaffe overcame his addiction (58:30)

Common habits that unknowingly lead to addiction (1:07:34)

Understanding the addiction of self-criticism (1:22:21)

Letting go of limiting beliefs and embracing self-evaluation (1:29:15)

The power of celebrating small wins (1:37:30)

Where to follow Dr. Jaffe’s work (1:44:08)

Also mentioned in this episode:

Unhooked: Free Yourself from Addiction Forever

How to Heal Your Body and Manifest Reality with Bruce Lipton

For more on Dr.Jaffe, follow him on Facebook, Instagram, X/Twitter,  Apple Podcast, LinkedIn, his Website, and other platforms, such as IGNTD™.

This episode is brought to you by Momentous, Cozy Earth, and Levels,

Optimize your energy and mental clarity with the Momentous Three: Protein, Omega-3s, and Creatine made by and used by the best. Head to livemomentous.com and use code DHRU for 35% off your first subscription.

Right now, get 40% off your Cozy Earth sheets. Just head over to cozyearth.com/dhru and use code DHRUP.

Right now, Levels is offering my listeners an additional 2 FREE months of the Levels annual Membership when you use my link, levels.link/DHRU. Make moves on your metabolic health with Levels today. Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is brought to you by Levels and Maui Nui.

When most people think about metabolic health, they think of weight management and steady energy. But here’s what often gets overlooked: metabolic health also plays a major role in sexual function and fertility.

Our hormones depend on a delicate balance—and when blood sugar spikes and crashes, that balance gets thrown off. The result? Not just weight gain, mood swings, and fatigue, but also a higher risk of erectile dysfunction, infertility, reduced sexual pleasure, and more.

Today on The Dhru Purohit Show, we’re bringing you a special compilation episode featuring Dhru’s conversations with experts on how sexual health can reflect your overall metabolic health.

Dr. Casey Means explains that blood flow, hormones, and psychology are the three pillars of good sexual function. She shares how diet impacts all three through a hormonal cascade, along with effects on nitric oxide and neurotransmitter production.

Dr. Rena Malik dives into the importance of a healthy sex life and the common challenges men and women face—from low libido and hormone imbalances to lifestyle factors that get in the way. She breaks down the science behind sexual health, including the roles of diet, exercise, and orgasms, and unpacks the key roadblocks that can prevent us from experiencing a truly fulfilling sex life.

Dr. Casey Means is a Stanford-trained physician, Co-founder of the metabolic health company Levels, and author of Good Energy. Her mission is to maximize human potential and reverse the epidemic of preventable chronic disease by empowering individuals with tools that foster a deep understanding of their bodies and support personalized, sustainable dietary and lifestyle choices.

Dr. Rena Malik is a board-certified urologist with a talent for dispelling medical misinformation, discussing intimate topics, and evidence-based discussions of taboo topics. Dr. Malik is also a  prominent reconstructive urologist treating bladder conditions, sexual dysfunction, pelvic pain, and hormone management.

In this episode, Dhru and his guests dive into:

Paying attention to your sexual and overall health (1:37)

The link between sex drive and metabolic function (5:49)

Three key ways metabolic and sexual health are connected (8:41)

Habits that restrict blood flow and negatively impact sex drive (14:21)

The alarming rate of fertility decline (18:50)

How metabolic health affects egg quality, sperm quality, and hormone balance (22:11)

The connection between sex, longevity, and a healthy lifespan (33:09)

How exercise boosts internal motivation and physical desire for sex (36:14)

The effects of a sedentary lifestyle on libido and sexual health (33:11)

Top factors interfering with a pleasurable sex life (37:39)

Hormonal and menopause-related challenges—and potential solutions (44:14)

Hormone therapy and its benefits for women’s libido (49:25)

Physical factors that can prevent enjoyment of sex (51:23)

Final thoughts (55:14)



Also mentioned:

Full episode with Dr. Casey Means

Full episode with Dr. Rena Malik

3 Ways metabolic health affects sexual function

This episode is brought to you by Levels and Maui Nui. 

Right now, Levels is offering my listeners an additional 2 FREE months of the Levels annual Membership when you use my link: levels.link/DHRU. Make moves on your metabolic health with Levels today.

Right now Maui Nui Venison is offering my listeners a limited collection of my favorite cuts and products. Just go to mauinuivenison.com/dhru to secure your access now —but hurry, supply is limited! Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is brought to you by Levels, BiOptimizers, and Birch Living. 

Traditionally, elevated LDL has been directly linked to a higher risk of cardiovascular disease. But today’s guest is on a mission to dig deeper. He’s raising both awareness and funding to explore the true relationship between LDL, ApoB, and heart disease—challenging long-held beliefs in the process. He joins us to share the results of his team’s groundbreaking study.

Today on The Dhru Purohit Show, Dhru sits down with Dave Feldman to discuss his team’s landmark study on LDL cholesterol and its implications for cardiovascular health. Dave shares the personal journey that led him to fund this research and what it means for how we approach and treat heart disease. He breaks down the surprising findings on how plaque progression really occurs—and the key questions that still need answers in future studies. Dave also outlines the most effective tests to assess your risk, along with how to interpret your scores based on age.

Dave Feldman is a software and platform engineer, entrepreneur, and founder of the Citizen Science Foundation. His life took a radical turn upon seeing his cholesterol skyrocket after adopting a ketogenic diet, and he became obsessed with understanding why this is common with those who are likewise leaner and more metabolically healthy. Through a series of self-experiments and partnering with formal researchers, he has since published the “Lipid Energy Model,” which may explain this phenomenon.

In this episode, Dhru and Dave dive into:

Dave’s mission and journey to pursue answers (00:30)

What mainstream medicine believes about high cholesterol (4:20)

The keto and carnivore view on cholesterol (6:00)

Dave's perspective and his groundbreaking research (7:45)

Why Dave’s research matters and its implications for cardiovascular disease prevention (15:57)

The factors that led to starting and releasing the study (18:23)

The surprising results of plaque progression (28:42)

What the results mean on a broad scale and how to configure the right type of diet (35:32)

Appropriate testing and optimal score ranges (45:32)

Factors that contribute to plaque progression (53:32)

Injury to cells and arterial lining—and what prevents repair (1:00:32)

The likely responses to the landmark study (1:23:47)

Advice on ApoB based on large-scale metabolic health concerns (1:38:32)

Critical takeaways (1:42:22)

Where to follow Dave and learn about his upcoming movie (1:45:32)

Also mentioned in this episode:

Plaque Begets Plaque, Not ApoB, JACC Journals

Citizen Science Foundation

For more on Dave, follow him on Instagram, Twitter/X, YouTube, his Website, and other platforms, such as Cholesterol Code.

This episode is brought to you by Levels, BiOptimizers, and Birch Living.

Right now, Levels is offering my listeners an additional 2 FREE months of the Levels annual Membership when you use my link: levels.link/DHRU. Make moves on your metabolic health with Levels today.

Go to bioptimizers.com/dhru now and enter promo code DHRU10 to get 10% off any order of Sleep Breakthrough and find out this month’s gift with purchase. 

Get 20% off your Birch Living mattress during their Spring Event—just head to birchliving.com/dhru today!  Learn more about your ad choices. Visit megaphone.fm/adchoices